27 dez. CAQUEXIA Apresentação de seminário na disciplina HSA Fundamentos Biológicos da Saúde Humana Docente responsável: Cláudia. 23 pacientes com macroadenomas hipofisários clinicamente não funcionantes , com Cancer-associated cachexia is the most important tumor-associated. Fibrodisplasia ossificante progressiva: relato de caso Fibrodysplasia ossificans progressiva: a case report · Directory of Open Access Journals (Sweden).

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Development of lutetium-labeled bombesin derivates: Bombesin BBN receptors – in particular, the gastrin-releasing peptide GRP receptor peptide – have been shown to be massively over expressed in several human tumors types, including prostate cancer, and could be an alternative as target for its treatment by radionuclide therapy RNT. A large number of BBN analogs had already been hipoifsario for this purpose and have shown to reduce tumor growth in mice.

Nevertheless, most of the studied analogs exhibit high abdominal accumulation, especially in pancreas. This abdominal accumulation may represent a problem in clinical use of radiolabeled bombesin analogs probably due to serious side effects to patients. The goal of the present work was to radiolabel a novel series of bombesin derivatives with lutetium and to evaluate the relationship between their structure and diagnostic-therapeutic activity for prostate tumor.

Preliminary studies were done to establish the ideal labeling conditions for obtaining the highest yield of labeled bombesin derivatives, determined by instant thin layer chromatography ITLC-SG and high performance liquid chromatography HPLC.

The stability of the preparations was evaluated either after storing at degree C or incubation in human serum at 37 degree C and the partition coefficient was determined in n: In vivo studies were performed in both healthy Balb-c and Nude mice bearing PC-3 xenografts, in order to characterize the biological properties of labeled peptides.

In vitro studies involved the evaluation of cold bombesin derivatives effect in PC-3 cells proliferation. Bombesin derivatives were successfully labeled with high yield at optimized conditions and exhibited high stability at 4 degree C.

Directory of Open Access Journals Sweden. Full Text Available Resumo: However, the molecular mechanism of tumor suppression is not yet understood. Estudo retrospectivo de 1. Mammary gland tumors are common in dogs and are the most common type of neoplasm of female dogs. There were 1, biopsy reports of mammary gland tumors during and necropsy reports of dogs with mammary tumors in Data about breed, gender, and. O estudo baseou-se em um universo de 6.

Aiming at a complete study on all neoplastic lesions in farm animals cattle, sheep, horses and swine, a retrospective review was performed covering a 24 years period at the Regional Diagnostic Laboratory of the Veterinary School in Acquexia, Southern Brazil. The analysis included the review of epidemiological data and the standardization of classification parameters considering current rules of international classification of tumors.

Six thousand two hundred and sixty seven samples were analyzed. The distribution among the species was: Prevalence studies as for the breed, sex, age and anatomical distribution of the tumors were analyzed. Lymphoma in cattle, squamous cell carcinoma in cattle and sheep, and sarcoids in horses were the tumors with higher incidence. Os tumores menores eram, na sua maioria, carcinomas.

Wilms tumor in adult: Wilms’ tumor is the renal tumor with cqauexia higher incidence on the childhood, however it rarely occurs in adults. In this report is related a hipofisaario case in a 52 years old man presenting intensive abdominal pain associated by nipofisario.

Abdominal ultrasound revealed expansive and complex lesion with indefinite contour in the left flank. Computed tomography of abdomen demonstrated solid lesion on antero-superior pole of the left kidney invading para-vertebral musculature, peri and para-renal spaces. Total nephrectomy and the histopathologic analysis were realized. A nephroblastoma Wilms’ tumor in stage II without anaplasia was diagnosed by the anatomopathological studies.


Narcolepsia sintomática em um cão com macroadenoma hipofisário

Local radiotherapy was applied. Thereafter was diagnosed pulmonary and hepatic metastasis, and then initiated the chemotherapy with adriamycin, actinomycin and vincristine. The prognosis of Wilms’ tumor is worse in adult and it requires an aggressive therapeutic and follow up. To develop a model to evaluate the effects of focal pulsed ultrasound US waves hipofisafio a source of heat for hhipofisario of murine subcutaneous implanted Walker tumor. An experimental, controlled, comparative study was conducted.

Twenty male Wistar rats g randomized in 2 equal groups G Hyperthermia were inoculated with Walker carcinosarcoma tumor. Tumor volume was measured on days 5, 8, 11, 14 e 17 post inoculation in both groups. Unpaired t-test was used for comparison. Um estudo experimental, controlado, comparativo foi realizado. Vinte ratos Wistar machos g divididos em dois hipofisxrio G Evaluation of the ocular protection for low intensity therapeutic lasers; Avaliacao da protecao ocular para lasers terapeuticos em baixa intensidade.

The low intensity laser therapy LILT has been extensively used in medicine and dentistry presenting positive effects.

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However, the laser radiation can also cause adverse effects. Due to the ocular focalization property, in the wavelength from to nm, the retina is more susceptible to damage by radiation than any other part of the human body.

Then, the ocular protection is frequently emphasized. This protection must attenuate the radiation to a safe level. The International Electrotechnical Commission IEC standard IEC suggests safety requirements caqufxia medical laser equipment, including the ocular protection, based on maximum permissible exposure levels.

terapeutico em tumores: Topics by

The aim of this study was to analyze the adequacy of the ocular protectors furnished by four laser equipment manufacturers, commercially available in Brazil, commonly used for LILT. For this purpose, the laser equipment and the respective ocular protectors were characterized. The adequacy was verified according to the IEC standards. It was found, among other results, ocular protectors attenuating to safe levels the radiation emitted by the respective laser equipment, however, presenting inadequate visual transmission.

Inefficient protection and protection indicated in cases where they were not necessary were also observed. To correlate the ophthalmic complications in patients with extra-orbital malignant tumors with the site of origin and histopathologic diagnosis of the tumors by. Spinal cord tumor in a patient with multiple sclerosis: Full Text Available The association between multiple MS sclerosis and cerebral gliomas has been sporadically reported in the literature, causing a long lasting discussion if these lesions occur coincidentally or if MS plaques may actually lead to the genesis of gliomas.

We report a 36 year old man who developed a rapid onset of right side weakness and loss of vision, having established a diagnosis of MS which was confirmed by CSF analysis and MRI. Nine years later he developed progressive tetraparesis, leading initially to suspicion of illness relapse and a demyelinating plaque in the spinal cord.

However, after MRI investigation, a spinal cord tumor was diagnosed. The patient underwent cervical spine laminotomy for microsurgical removal of the spinal cord tumor diagnosed as ependimoma.

The neurological deficits improved significantly. Tumores do tronco cerebral: Dos tumores intracranianos observados, 35 estavam localizados no tronco cerebral. Studies for investigation of new therapeutic modalities in tumoral biology should be based on previous experimental studies. Then, there are a great variety of tumoral experimental models today. Some investigations have been done necessary an adaptation of the tumoral model to the needing of the studies biological and pathological.


So, in our laboratory, we looked for a tumoral hepatic model for experimental studies with the following characteristics: Data of the literature took us the search of the hepatic tumor VX-2, in rabbits.

In this article we discussed the advantages of use this experimental model and its introduction in our country. Experimental hepatic tumor VX-2 in rabbit. Implantation of the model in Brazil. Full Text Available Cystadenoma of salivary glands is an uncommon benign neoplasm that presents intraluminal papillary projections.

The authors describe one case of cystadenoma located in the buccal mucosa and highlight its histomorphological features and differential diagnosis. Full Text Available A case of suprasellar germ cell tumor is described in a 6-year -old Airedale Terrier bitch that presented behavioral changes and abrupt onset of blindness.

The neoplasm compressed the ventral surface of the cerebrum from the level of basal ganglia to the mesencephalon. Histologically the neoplasm consisted of nests and trabeculae of round to polygonal cells that occasionally surround tubules and cysts formed by columnar cells.

Neoplastic cells are immunopositive for cytokeratin and alpha-fetoprotein.

The diagnosis was based on location, histological appearance and on the immunohistochemical staining. Adenomatoid odontogenic tumor is a relatively uncommon lesion, which affects mainly individuals of the female during the second decade due, showing as a site of predilection for the anterior region of the maxilla presenting lesion usually associated with the crown of a tooth incluso.

Os authors report a case of an adenomatoid odontogenic tumor in the anterior region of mandible, together with their clinical, radiographic and histological and its surgical treatment. Full Text Available Canine transmissible venereal tumor TVT is a round cell neoplasm occurring on the external genital mucosa of male and female dogs. Transmission is by cell implantation during coitus, licking, or other interaction between an affected dog and a susceptible host.

Metastasis of the tumor rarely occurs. This report describes an unusual presentation of TVT with intraocular involvement and inguinal lymph nodes metastasis. The subject was a six-year-old, intact, male, Brazilian Terrier dog with a history of abnormal masses in the right eye, penis and several subcutaneous nodules in the inguinal area.

Histopathological examination of the eye specimens as well as cytologic examination of penile mass and subcutaneous nodules revealed similar findings. The examination revealed round cells containing a large nuclei with prominent, central located nucleoli and a pale cytoplasm containing few small, clear round vacuoles.

Histologically, the subcutaneous nodules in the inguinal area were lymph nodes. The diagnosis of TVT with intraocular involvement and lymph nodes metastasis was based on clinical, cytologic and histopathologic findings.

The therapeutic role of the dacryocystography in patients with epiphora: Faculdade de Ciencias Medicas. We describe three cases of patients that presented epiphora having been submitted the accomplishment of dacryocystographic study, which ones turned asymptomatic after the accomplishment of the exam, without any other procedure or medicine.

The therapeutic potential of the method is stood out, once the literature on this subject is scarce in children and none in adults. To study factors possibly associated with tumor contamination in the biopsy caqudxia of primary malignant bone tumors. Thirty-five patients who underwent surgical treatment with diagnoses of osteosarcoma, Ewing’s tumor and. Glioma supratentorial de baixo grau em adulto: